Targeting Conserved Water Molecules: Design of 4-Aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 Inhibitors Using Fragment-Based Screening and Structure-Based Optimization

Targeting Conserved Water Molecules: Design of 4-Aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 Inhibitors Using Fragment-Based Screening and Structure-Based Optimization

Davies, N. G. M. et al., Bioorg. Med. Chem. 2012, 20, 6770–6789

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